This paper analyses the quantitative research on disabled persons' social inclusion patterns in the Croatian employment sector. Croatian Employment Service and Croatian National Institute for Expertise, Professional Rehabilitation and Employment of Persons with Disabilities aggregated open source data have been used to calculate the national structure and movement of employed and unemployed persons with disabilities in the Croatian employment sector from 2005-2022. The paper used a statistical analysis of the dynamic change of employed and unemployed persons with disabilities in the period from 2005 to 2022 in monitoring changes in the number of employed and unemployed persons with disabilities. The shares of the number of employed persons in the total number of persons with disabilities and the shares of the number of unemployed persons in the total number of persons with disabilities were calculated. Statistical coefficients were also presented, showing the ratio of the number of unemployed persons with disabilities to employed persons with disabilities. The analysis results show a positive trend in the employment of persons with disabilities in the Croatian employment sector from 2005 to 2022. Observing the direct relationship between employment and unemployment of persons with disabilities, there is an encouraging trend. Since 2005, the number of unemployed per employed person with disabilities has been decreasing year by year. There is a noticeable reverse trend of decrease in the period of the great economic crisis 2008-2011 and a discrepancy in 2020 at the time of the COVID-19 pandemic, indicating the employment sector reaction to pressures of significant socio- economic changes on the employment rates of people with disabilities, which are consequently negatively reflected and primarily affecting employment status of vulnerable social groups. Finally, research and practical implications, limitations and further research recommendations are discussed.